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ASB2 Polyclonal Antibody
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Product Details
BS-2835R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ASB2, amino acids 501-587.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ankyrin repeat and SOCS box protein 2; ankyrin repeat and SOCS box-containing protein 2; ankyrin repeat and SOCS box-containing protein 2a; ankyrin repeat-containing SOCS box protein 2; ASB-2; asb2; asb2 {ECO:0000312|EMBL:AAH85882.1}; MGC40044; unnamed protein product
Gene Aliases: 1110008E15Rik; ASB-2; ASB2
UniProt ID: (Human) Q96Q27, (Mouse) Q8K0L0, (Rat) Q5U2S6
Entrez Gene ID: (Human) 51676, (Mouse) 65256, (Rat) 299266
heart looping
ubiquitin-dependent protein catabolic process
signal transduction
skeletal muscle atrophy
protein ubiquitination
actin cytoskeleton organization
intracellular signal transduction
skeletal muscle cell differentiation
dendritic cell migration
proteasome-mediated ubiquitin-dependent protein catabolic process
cardiac muscle cell differentiation
cardiac muscle cell development
podosome assembly
regulation of barbed-end actin filament capping
protein polyubiquitination
positive regulation of defense response to virus by host
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
myoblast differentiation
mitophagy in response to mitochondrial depolarization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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