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Invitrogen
ASB2 Polyclonal Antibody
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Product Details
PA5-50361
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to a region derived from internal residues of human ankyrin repeat and SOCS box containing 2
Conjugate
Form
Liquid
Concentration
2.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total ASB2 protein.
Target Information
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ankyrin repeat and SOCS box protein 2; ankyrin repeat and SOCS box-containing protein 2a; ASB-2; MGC40044
Gene Aliases: ASB-2; ASB2
UniProt ID: (Human) Q96Q27
Entrez Gene ID: (Human) 51676
protein polyubiquitination
positive regulation of defense response to virus by host
signal transduction
intracellular signal transduction
skeletal muscle cell differentiation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
myoblast differentiation
mitophagy in response to mitochondrial depolarization
xenophagy
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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