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Invitrogen
ASGR2 Polyclonal Antibody
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FIGURE: 1 / 1
ASGR2 Antibody (PA5-89547) in WB
Western blot analysis of ASGR2 in extracts of various cell lines. Samples were incubated with ASGR2 Polyclonal antibody (Product # PA5-89547) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-89547
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 131-287 of human ASGR2 (NP_5504351)
Conjugate
Form
Liquid
Concentration
2.84 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VDLRFVACQM ELLHSNGSQR TCCPVNWVEH QGSCYWFSHS GKAWAEAEKY CQLENAHLVV INSWEEQKFI VQHTNPFNTW IGLTDSDGSW KWVDGTDYRH NYKNWAVTQP DNWHGHELGG SEDCVEVQPD GRWNDDFCLQ VYRWVCEKRR NATGEVA; Positive Samples: Mouse liver, Rat liver; Cellular Location: Membrane, Single-pass type II membrane protein
Target Information
ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANCO-2; ANCO1; ASGP-R 2; ASGPR 2; Asialoglycoprotein receptor 2; GAC-1; Hepatic lectin 2; hepatic lectin 2 RHL2; hepatic lectin 2, RHL2; Hepatic lectin R2/3; HL-2; mHL-2; Nbla00144; RHL-2
Gene Aliases: ASGPR2; Asgr; Asgr-2; Asgr2
UniProt ID: (Mouse) P24721, (Rat) Q5M8C9
Entrez Gene ID: (Mouse) 11890, (Rat) 29403
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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