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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ASGR2 Antibodies

          Invitrogen

          ASGR2 Polyclonal Antibody

          View all (13) ASGR2 antibodies

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          Cite ASGR2 Polyclonal Antibody

          • Antibody Testing Data (1)
          ASGR2 Antibody in Western Blot (WB)
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          ASGR2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          ASGR2 Antibody (PA5-92863) in WB

          Western blot analysis of ASGR2 in extracts of HepG2 cells. Samples were incubated with ASGR2 Polyclonal antibody (Product # PA5-92863) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ASGR2 Antibody in Western Blot (WB)

          Product Details

          PA5-92863

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 58-311of human ASGR2 (NP_550435.1).

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1.62 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2806522

          Product Specific Information

          Immunogen sequence: CFSLLALSFN ILLLVVICVT GSQSEGHGGA QLQAELRSLK EAFSNFSSST LTEVQAISTH GGSVGDKITS LGAKLEKQQQ DLKADHDALL FHLKHFPVDL RFVACQMELL HSNGSQRTCC PVNWVEHQGS CYWFSHSGKA WAEAEKYCQL ENAHLVVINS WEEQKFIVQH TNPFNTWIGL TDSDGSWKWV DGTDYRHNYK NWAVTQPDNW HGHELGGSED CVEVQPDGRW NDDFCLQVYR WVCEKRRNAT GEVA

          Positive Samples: HepG2; Cellular Location: Membrane, Single-pass type II membrane protein

          Target Information

          ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: ANCO-2; ANCO1; ASGP-R 2; Asialoglycoprotein receptor 2; C-type lectin domain family 4 member H2; GAC-1; HBxAg-binding protein; Hepatic lectin H2; HL-2; Nbla00144

          View more View less

          Gene Aliases: ASGP-R2; ASGPR2; ASGR2; CLEC4H2; HBXBP; HL-2

          View more View less

          UniProt ID: (Human) P07307

          View more View less

          Entrez Gene ID: (Human) 433

          View more View less

          Function(s)
          asialoglycoprotein receptor activity protein binding carbohydrate binding membrane traffic protein
          Process(es)
          receptor-mediated endocytosis cell surface receptor signaling pathway glycoprotein metabolic process bone mineralization regulation of protein stability lipid homeostasis
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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