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FIGURE: 1 / 1
ASGR2 Antibody (PA5-92863) in WB
Western blot analysis of ASGR2 in extracts of HepG2 cells. Samples were incubated with ASGR2 Polyclonal antibody (Product # PA5-92863) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-92863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 58-311of human ASGR2 (NP_550435.1).
Conjugate
Form
Liquid
Concentration
1.62 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806522
Product Specific Information
Immunogen sequence: CFSLLALSFN ILLLVVICVT GSQSEGHGGA QLQAELRSLK EAFSNFSSST LTEVQAISTH GGSVGDKITS LGAKLEKQQQ DLKADHDALL FHLKHFPVDL RFVACQMELL HSNGSQRTCC PVNWVEHQGS CYWFSHSGKA WAEAEKYCQL ENAHLVVINS WEEQKFIVQH TNPFNTWIGL TDSDGSWKWV DGTDYRHNYK NWAVTQPDNW HGHELGGSED CVEVQPDGRW NDDFCLQVYR WVCEKRRNAT GEVA
Positive Samples: HepG2; Cellular Location: Membrane, Single-pass type II membrane protein
Target Information
ASGR2 is a cell surface receptor that binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface. There are four alternatively spliced transcript variants of this gene. This gene has multiple polyadenylation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ANCO-2; ANCO1; ASGP-R 2; Asialoglycoprotein receptor 2; C-type lectin domain family 4 member H2; GAC-1; HBxAg-binding protein; Hepatic lectin H2; HL-2; Nbla00144
Gene Aliases: ASGP-R2; ASGPR2; ASGR2; CLEC4H2; HBXBP; HL-2
UniProt ID: (Human) P07307
Entrez Gene ID: (Human) 433
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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