|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 284 and 610 of Human ASH2L|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30298 targets ASH2L in WB applications and shows reactivity with Human samples.
The PA5-30298 immunogen is recombinant fragment corresponding to a region within amino acids 284 and 610 of Human ASH2L.
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ASH2; ash2 (absent, small, or homeotic)-like; ASH2-like protein; ASH2L1; ASH2L2; Bre2; Set1/Ash2 histone methyltransferase complex subunit ASH2
Gene Aliases: ASH2; ASH2L; ASH2L1; ASH2L2; Bre2
UniProt ID: (Human) Q9UBL3
Entrez Gene ID: (Human) 9070
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