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Invitrogen
ASPH Polyclonal Antibody
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Product Details
PA5-63702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ASPH. Recombinant protein control fragment (Product #RP-101597).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DYEEVLGKLG IYDADGDGDF DVDDAKVLLG LKERSTSEPA VPPEEAEPHT EPEEQVPVEA EPQNIEDEAK EQIQSLLHEM VHAEHVEGED LQQEDGPT
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 73%.
Target Information
ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins. This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A beta H-J-J; ASP beta-hydroxylase; Aspartate beta-hydroxylase; Aspartyl/asparaginyl beta-hydroxylase; ASPH6; cardiac junctin; Humbug; junctate; junctional sarcoplasmic reticulum protein; junctional sarcoplasmic reticulum protein; calsequestrin binding protein; Peptide-aspartate beta-dioxygenase; unnamed protein product
Gene Aliases: AAH; ASPH; BAH; CASQ2BP1; FDLAB; HAAH; JCTN; junctin
UniProt ID: (Human) Q12797
Entrez Gene ID: (Human) 444
detection of calcium ion
muscle contraction
pattern specification process
cell proliferation
negative regulation of cell proliferation
positive regulation of calcium ion transport into cytosol
regulation of cell communication by electrical coupling
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
regulation of protein stability
activation of store-operated calcium channel activity
response to ATP
limb morphogenesis
positive regulation of proteolysis
positive regulation of transcription, DNA-templated
regulation of cytosolic calcium ion concentration
calcium ion homeostasis
palate development
face morphogenesis
calcium ion transmembrane transport
cellular response to calcium ion
positive regulation of intracellular protein transport
regulation of protein depolymerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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