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Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase family AAA domain-containing protein 5; ATPase family, AAA domain containing 5; chromosome fragility associated gene 1; Chromosome fragility-associated gene 1 protein; enhanced level of genomic instability 1 homolog; FLJ12735
Gene Aliases: ATAD5; C130052G03Rik; C17orf41; ELG1; FRAG1; Gm17; RGD1561464
UniProt ID: (Human) Q96QE3, (Mouse) Q4QY64
Entrez Gene ID: (Human) 79915, (Mouse) 237877, (Rat) 303348
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