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ATAD5 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
BS-7656R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ATAD5, amino acids 1151-1250.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chromosome fragility associated gene 1; chromosome fragility-associated gene 1 protein; enhanced level of genomic instability 1 homolog; FLJ12735; FRAG1; Ctf18/Rad24/Elg1-related gene 1; unnamed protein product
Gene Aliases: C130052G03Rik; C17orf41; ELG1; FRAG1; Gm17; RGD1561464
UniProt ID: (Human) Q96QE3, (Mouse) Q4QY64
Entrez Gene ID: (Human) 79915, (Rat) 303348, (Mouse) 237877
cellular response to DNA damage stimulus
biological_process
cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of B cell proliferation
nuclear DNA replication
signal transduction in response to DNA damage
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of DNA replication
positive regulation of isotype switching to IgG isotypes
positive regulation of DNA metabolic process
regulation of cell cycle phase transition
regulation of mitotic cell cycle phase transition
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of cell cycle G2/M phase transition
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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