This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.
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Protein Aliases: APG10; APG10-like; APG10L; ATG10 autophagy related 10 homolog; autophagy related 10 homolog; autophagy-related 10; Autophagy-related protein 10; mAPG10; PP12616; Ubiquitin-like-conjugating enzyme ATG10
Gene Aliases: 5330424L23Rik; 5430428K15Rik; Agp10; AI852123; APG10; APG10L; Apg10p; ATG10; Atg10l; PP12616