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Invitrogen
ATG4A Polyclonal Antibody
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FIGURE: 1 / 1
ATG4A Antibody (PA5-47614) in WB
Western blot analysis of ATG4A in HUVEC human umbilical vein endothelial cells, MCF‚7 human breast cancer cell line, and human skeletal muscle tissue. Samples were incubated in ATG4A polyclonal antibody (Product # PA5-47614) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Sheep IgG secondary antibody. A specific band was detected for ATG4A at approximately 48 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
PA5-47614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant human ATG4A Glu2-Val398
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human ATG4GB is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APG4 autophagy 4 homolog A; ATG4 autophagy related 4 homolog A; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagin 2; Autophagin-2; Autophagy-related cysteine endopeptidase 2; Autophagy-related protein 4 homolog A; Cysteine protease ATG4A; hAPG4A; HsAPG4A; MGC107179; unnamed protein product
Gene Aliases: APG4A; ATG4A; AUTL2; HsAPG4A
UniProt ID: (Human) Q8WYN0
Entrez Gene ID: (Human) 115201
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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