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Suggested positive control: antigen standard for ATOX1 (transient overexpression lysate), HeLa nuclear extracts.
ATOX1 is a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATX1 antioxidant protein 1 homolog; Copper transport protein ATOX1; Metal transport protein ATX1
Gene Aliases: ATOX1; ATX1; HAH1
UniProt ID: (Human) O00244
Entrez Gene ID: (Human) 475
Molecular Function:
chaperone
transfer/carrier protein
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