Immunogen sequence: LMQTVDPYTP DYQDQLRSPG VTLRPDVYGE KGLEIVYNVS DNRTWADLTQ TLHAFLAGYS PAAQEDSINC TSEQYFFQES FRAPNHTKFS CKFTADMLQN CSGLADPNFG FEEGKPCFII KMNRIVKFLP SNGSAPRVDC AFLDQPRELG QPLQVKYYPP NGTFSLHYFP YYGKKAQPHY SNPLVAAKLL NIPRNAEVAI VCKVMAEHVT FNNPHDPYEG KVEFKLKIEK; Positive Samples: LO2, SW620, NCI-H460, Mouse small intestine, Mouse liver, Mouse heart, Mouse pancreas, Rat stomach; Cellular Location: Cell membrane, Single-pass type II membrane protein
The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subunit. Like the ubiquitous sodium/potassium ATPase, the hydrogen/potassium ATPase consists of a large transmembrane catalytic subunit, termed the alpha- subunit which contains sites for ATP binding and phosphorylation, and an associated smaller glycoprotein, termed the beta-subunit which may play a role in maintaining the structural and functional integrity of the complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATPase H+K+-transporting beta / (gastric HK-ATPase beta subunit) defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide, gastric specific; Gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+ ATPase beta subunit; gastric hydrogen-potassium ATPase, beta; H+,K+-ATPase; H+/K+-ATPase beta; H,K-ATPase-Beta; potassium-transporting ATPase beta chain; Potassium-transporting ATPase subunit beta; Proton pump beta chain
Gene Aliases: ATP4B; ATP6B; AV080843; S76401S1