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Invitrogen
ATP4B Polyclonal Antibody
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FIGURE: 1 / 1
ATP4B Antibody (PA5-87635) in WB
Western blot analysis of ATP4B in extracts of various cell lines. Samples were incubated with ATP4B Polyclonal antibody (Product # PA5-87635) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-87635
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human ATP4B (NP_0006961)
Conjugate
Form
Liquid
Concentration
0.93 mg/mL
Amount
93 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LMQTVDPYTP DYQDQLRSPG VTLRPDVYGE KGLEIVYNVS DNRTWADLTQ TLHAFLAGYS PAAQEDSINC TSEQYFFQES FRAPNHTKFS CKFTADMLQN CSGLADPNFG FEEGKPCFII KMNRIVKFLP SNGSAPRVDC AFLDQPRELG QPLQVKYYPP NGTFSLHYFP YYGKKAQPHY SNPLVAAKLL NIPRNAEVAI VCKVMAEHVT FNNPHDPYEG KVEFKLKIEK; Positive Samples: LO2, SW620, NCI-H460, Mouse small intestine, Mouse liver, Mouse heart, Mouse pancreas, Rat stomach; Cellular Location: Cell membrane, Single-pass type II membrane protein
Target Information
The hydrogen/potassium ATPase, or gastric proton pump, belongs to a family of P-type cation-transporting ATPases. This family of ATPases shares a number of functional and structural similarities including the common feature of consisting of an alpha and beta subunit. Like the ubiquitous sodium/potassium ATPase, the hydrogen/potassium ATPase consists of a large transmembrane catalytic subunit, termed the alpha- subunit which contains sites for ATP binding and phosphorylation, and an associated smaller glycoprotein, termed the beta-subunit which may play a role in maintaining the structural and functional integrity of the complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATPase H+/K+ transporting beta subunit; ATPase H+K+-transporting beta / (gastric HK-ATPase beta subunit) defined by SSR; ATPase, H+,K+-transporting, beta / (gastric H,K-ATPase beta subunit), defined by SSR; ATPase, H+/K+ exchanging, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide; ATPase, H+/K+ transporting, beta polypeptide, gastric specific; Gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+ ATPase beta subunit; gastric hydrogen-potassium ATPase, beta; H+,K+-ATPase; H+/K+ ATPase beta; H+/K+-ATPase beta; H,K-ATPase-Beta; potassium-transporting ATPase beta chain; Potassium-transporting ATPase subunit beta; Proton pump beta chain
Gene Aliases: ATP4B; ATP6B; AV080843; S76401S1
UniProt ID: (Human) P51164, (Rat) P18598, (Mouse) P50992
Entrez Gene ID: (Human) 496, (Rat) 24217, (Mouse) 11945
ion transport
potassium ion transport
sodium ion transport
cellular sodium ion homeostasis
cell adhesion
cellular potassium ion homeostasis
response to lipopolysaccharide
sodium ion export from cell
pH reduction
potassium ion transmembrane transport
hydrogen ion transmembrane transport
potassium ion import across plasma membrane
gastric acid secretion
response to organonitrogen compound
transport
regulation of proton transport
proton transport
protein glycosylation in endoplasmic reticulum
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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