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Invitrogen
AUTS2 Monoclonal Antibody (CL7084)
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Product Details
MA5-31447
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
CL7084
Immunogen
Synthetic peptide corresponding to Human AUTS2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GISPLPGGER FPYPSFHWD
Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.
Target Information
AUTS2 also named as FBRSL2 or autism susceptibility candidate 2 is a 1259 amino acid protein, which belongs to the AUTS2 family. AUTS2 is highly expressed in brain, kidney and skeletal muscle. AUTS2 exists as four isoforms produced by alternative splicing events and is encoded by a gene located on human chromosome 7. The molecular weight of AUTS2 isoform is 65-70 kDa in the brain. The functional role of AUTS2 is not well known, although some studies have identified a putative role in transcriptional regulation during neuronal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: autism susceptibility; autism susceptibility candidate 2; Autism susceptibility gene 2 protein; Autism susceptibility gene 2 protein homolog; autism-related protein 1; AUTS2, activator of transcription and developmental regulator; construct rescued the AUTS2 knockdown phenotype in zebrafish; encoded by an alternative transcriptional start site in exon 9; KIAA0442; unnamed protein product
Gene Aliases: 2700063G02Rik; A730011F23Rik; AUTS2; D830032G16Rik; FBRSL2; KIAA0442; MRD26
UniProt ID: (Human) Q8WXX7, (Mouse) A0A087WPF7
Entrez Gene ID: (Human) 26053, (Mouse) 319974
neuron migration
positive regulation of lamellipodium assembly
actin cytoskeleton organization
positive regulation of Rac protein signal transduction
positive regulation of transcription from RNA polymerase II promoter
axon extension
dendrite extension
positive regulation of histone H3-K4 methylation
righting reflex
innate vocalization behavior
positive regulation of histone H4-K16 acetylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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