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Invitrogen
AZGP1 Polyclonal Antibody
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FIGURE: 1 / 3
AZGP1 Antibody (PA5-13580) in IHC (P)
Immunohistochemistry analysis of AZGP1 in formalin fixed and paraffin embedded human prostate carcinoma. Samples were incubated with AZGP1 polyclonal antibody (Product # PA5-13580) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-13580
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 5-32 amino acids from the N-terminal region of human AZGP1
Conjugate
Form
Liquid
Concentration
2.0 mg/mL
Amount
800 µg
Purification
Size-exclusion - Dialysis, Ammonium sulfate precipitation
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-2-glycoprotein, zinc; testicular tissue protein Li 227; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; Zinc α 2 glycoprotein; Zinc α2glycoprotein; Zinc-alpha-2-glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; zn-alpha-2-glycoprotein; Zn-alpha-2-GP; Zn-alpha2-glycoprotein
Gene Aliases: AZGP1; ZA2G; ZAG; ZNGP1
UniProt ID: (Human) P25311
Entrez Gene ID: (Human) 563
detection of chemical stimulus involved in sensory perception of bitter taste
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
immune response
cell adhesion
negative regulation of cell proliferation
protein transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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