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          • Primary Antibodies ›
          • Aconitase 2 Antibodies

          Invitrogen

          Aconitase 2 Polyclonal Antibody

          1 Reference
          View all (22) Aconitase 2 antibodies

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          Cite Aconitase 2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          Aconitase 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Aconitase 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Aconitase 2 Antibody (PA5-19269) in IHC (P)

          Immunohistochemistry analysis of Aconitase 2 in human breast. Samples were incubated with Aconitase 2 polyclonal antibody (Product # PA5-19269) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          Aconitase 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Aconitase 2 Antibody in Western Blot (WB)
          Aconitase 2 Antibody in Western Blot (WB)
          Aconitase 2 Polyclonal Antibody

          Product Details

          PA5-19269

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.01-0.03 µg/mL
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          3-5 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Pig, Rat

          Published species

          Yeast

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (QDTYQHPPKDSSGQH) corresponding to the internal amino acids of ACO2 (aa 541-555).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          100 µg

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10978002

          Product Specific Information

          This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

          Target Information

          The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: ACO2; Aconitase; aconitase 2, mitochondrial; Aconitate hydratase, mitochondrial; Citrate hydro-lyase; epididymis secretory sperm binding protein Li 284; heart aconitase; heart aconitase precursor; MGC20605; MGC33908; mitochondrial aconitase; mitochondrial aconitase (nuclear aco2 gene); RP3-347H13.8; unnamed protein product

          View more View less

          Gene Aliases: Aco-2; ACO2; Aco3; ACONM; D10Wsu183e; HEL-S-284; ICRD; OCA8; OPA9

          View more View less

          UniProt ID: (Human) Q99798, (Pig) P16276, (Rat) Q9ER34, (Mouse) Q99KI0

          View more View less

          Entrez Gene ID: (Human) 50, (Pig) 396999, (Rat) 79250, (Mouse) 11429

          View more View less

          Function(s)
          aconitate hydratase activity iron ion binding lyase activity metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding citrate dehydratase activity protein binding 3 iron, 4 sulfur cluster binding hydratase
          Process(es)
          generation of precursor metabolites and energy tricarboxylic acid cycle citrate metabolic process isocitrate metabolic process metabolic process
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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