This antibody is predicted to react with bovine, chicken, canine, equine, hamster, mouse, porcine, non-human primate, rat, rabbit and Xenopus, yeast and zebrafish based on sequence homology.
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACTC1; Actin, alpha cardiac muscle 1; Actin, alpha cardiac muscle 1, intermediate form; actin, beta; Actin, cytoplasmic 1; Actin, cytoplasmic 1, N-terminally processed; Alpha-cardiac actin; Atcb; beta cytoskeletal actin; Beta-actin; PS1TP5-binding protein 1
Gene Aliases: ACTB; ACTC; ACTC1; ASD5; BRWS1; CMD1R; CMH11; LVNC4; PS1TP5BP1