Immunogen sequence: KPEKPSTLQR PQETVIRELQ PQQQPRTIER RDLQYITVSK EELSSGDSLS PDPWKRDAKE KLEKQQQMHI VDMLSKEIQE LQSKPDRSAE ESDRLRKLML EWQ
AFDN belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.
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Protein Aliases: AF-6; AF6; Afadin; Afadin adherens junction formation factor; ALL1-fused gene from chromosome 6 protein; MLLT4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4; Protein AF-6
Gene Aliases: AF6; AFDN; MLL-AF6; MLLT4
UniProt ID: (Human) P55196
Entrez Gene ID: (Human) 4301