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Aha1 Polyclonal Antibody
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FIGURE: 1 / 1
Aha1 Antibody (100-401-E82) in WB
Western Blot of Rabbit anti-Aha1 antibody. Lane 1: A431 lysate. Lane 2: A549 lysate. Lane 3: HCT116 lysate. Lane 4: Hela lysate. Lane 5: Hek293 lysate. Lane 6: HepG2 lysate. Lane 7: HL-6D lysate. Lane 8: HUVEC lysate. Lane 9: Jurkat lysate. Lane 10: MCF7 lysate. Lane 11: PC3 lysate. Lane 12: T98G lysate. Lane 13: Rat Brain lysate. Load: 1 µg per lane. Primary antibody: Aha1 antibody at 1:1,000 for overnight at 4&(8)304;C. Secondary antibody: Goat anti Rabbit IgG HRP at 1:10,000 for 30 min at RT. Block: 5% Blotto overnight at 4&(8)304;C. Pr... View More
Product Details
100-401-E82
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Aha1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with Mouse Aha1.
Conjugate
Form
Liquid
Concentration
85 mg/mL
Amount
8.5 mg
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activator of 90 kDa heat shock protein ATPase homolog 1; Aha 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; AHA1, activator of heat shock protein ATPase homolog 1; AHSA 1; p38; SHSA1; unnamed protein product
Gene Aliases: AHA1; AHSA1; BC023857; C14orf3; hAha1; HSPC322; p38
UniProt ID: (Human) O95433, (Mouse) Q8BK64
Entrez Gene ID: (Human) 10598, (Rat) 681996, (Mouse) 217737
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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