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Invitrogen
Annexin V Polyclonal Antibody
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FIGURE: 1 / 10
Annexin V Antibody (PA5-27872) in WB
Western blot was performed using Anti- Annexin V Polyclonal Antibody (Product # PA5-27872) and a 35 kDa band corresponding to Annexin V was observed across the cell lines tested. Whole cell extracts (30 µg) of HeLa (Lane 1), MCF-7 (Lane 2), MDA-MB231 (Lane 3), Hep G2 (Lane 4), tissues extracts of Mouse Liver( Lane 5), Mouse Skeletal Muscle (Lane 6) and Rat Skeletal Muscle (Lane 7) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Prod... View More
Product Details
PA5-27872
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Annexin V. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, GL261, C8D30, NIH-3T3, Raw 264.7, PC-12, Rat2.
Predicted reactivity: Mouse (93%), Rat (91%), Dog (98%), Chimpanzee (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Anchorin CII; annexin 5; Annexin A5; Annexin V; Annexin-5; anticoagulant precursor (5' end put.); putative; ANXA5; Calphobindin I; CBP-I; CPB-I; Endonexin II; epididymis secretory protein Li 7; Lipocortin V; lipocortin-V; PAP-I; Placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; Thromboplastin inhibitor; unnamed protein product; VAC-alpha; Vascular anticoagulant-alpha
Gene Aliases: ANX5; ANXA5; CPB-I; ENX2; HEL-S-7; LC5; PP4; R74653; RPRGL3; VAC-alph
UniProt ID: (Human) P08758, (Mouse) P48036, (Rat) P14668
Entrez Gene ID: (Human) 308, (Mouse) 11747, (Rat) 25673
signal transduction
blood coagulation
hemostasis
negative regulation of apoptotic process
negative regulation of coagulation
positive regulation of defense response to virus by host
response to organic substance
negative regulation of blood coagulation
positive regulation of apoptotic process
protein homooligomerization
response to calcium ion
mitophagy in response to mitochondrial depolarization
regulation of sperm motility
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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