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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 9 and 274 of Human AspRS|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30666 targets AspRS in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30666 immunogen is recombinant fragment corresponding to a region within amino acids 9 and 274 of Human AspRS.
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. It is a mitochondrial enzyme that specifically aminoacylates aspartyl-tRNA. Mutations in this gene are associated with leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation (LBSL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
aspartate tRNA ligase 2; aspartate tRNA ligase 2, mitochondrial; aspartate--tRNA ligase; aspartyl-tRNA synthetase; aspartyl-tRNA synthetase, mitochondrial; ASPRS; LBSL; mitochondrial; MT-ASPRS; RP3-383J4.2
ASPRS; DARS2; LBSL; MT-ASPRS