The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
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Protein Aliases: AIK; ARK 1; ARK-1; ARK1; AURA; AURKA; Aurora 2; Aurora A; Aurora family kinase 1; Aurora kinase A; Aurora related kinase 1; aurora-A; aurora-related kinase 1; Aurora/IPL1 related kinase 1; aurora/IPL1-like kinase; Aurora/IPL1-related kinase 1; AURORA2; Breast tumor amplified kinase; Breast tumor-amplified kinase; BTAK; hARK1; Ipl1- and aurora-related kinase 1; protein phosphatase 1, regulatory subunit 47; ratAurA; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 6; Serine/threonine-protein kinase aurora-A; Serine/threonine-protein kinase Ayk1; STK15; STK6; STK7
Gene Aliases: AIK; Airk; AIRK1; ARK-1; ARK1; AU019385; AURA; AURKA; Aurora-A; AW539821; AYK1; BTAK; IAK; IAK1; PPP1R47; STK15; STK6; STK7