AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.
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Protein Aliases: AXL oncogene; AXL transforming sequence/gene; Tyrosine-protein kinase receptor UFO; Tyrosine-protein kinase receptor UFO precursor
Gene Aliases: ARK; AXL; JTK11; Tyro7; UFO
UniProt ID: (Human) P30530
Entrez Gene ID: (Human) 558