The beta-1,3 galactosyltransferase( beta3GalT) gene family encodes a set of type II transmembrane glycoproteins that are catalytically diverse and use different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine ) to catalyze the addition of an activated monosaccharide to a terminal lactose. The protein coding sequences for beta-1,3-Gal-T genes comprise a single exon and are distantly related to the Drosophila Brainiac gene. The beta-1,4-galactosyltransferase ( beta4GalT) gene family encodes type II membrane-bound glycoproteins that show exclusive specificity for the donor substrate, UDP-galactose. beta-1,4Gal-T genes transfer galactose in a beta-1,4 linkage to similar acceptor.
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Protein Aliases: b4Gal-T3; Beta-1,4-galactosyltransferase 3; beta-1,4-galactosyltransferase III; Beta-1,4-GalTase 3; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3; Beta-N-acetylglucosaminyl-glycolipid4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide4-galactosyltransferase; beta4Gal-T3; beta4GalT-III; N-acetyllactosamine synthase; Nal synthase; Neolactotriaosylceramide beta-1,4-galactosyltransferase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3; beta-1,4-galactosyltransferase III; beta4GalT-III; expressed sequence tag mouse EST 6; UDP-galactose:beta-N-acetylglucosamine; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3
Gene Aliases: 9530061M23Rik; AA104562; AW125175; B4GALT3; beta4Gal-T3; ESTM26; ESTM6; R74981
Molecular Function: glycosyltransferase