This antibody is specific for isoform A of Bap29.
A suggested positive control is human heart tissue lysate.
PA5-20195 can be used with blocking peptide PEP-0325.
Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.
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Protein Aliases: B-cell receptor-associated protein 29; B-cell receptor-associated protein BAP29; BCR-associated protein 29
Gene Aliases: AW208404; BAP29; BCAP29