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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • BAZ2A Antibodies

          Active Motif

          BAZ2A Polyclonal Antibody

          1 Reference
          View all (10) BAZ2A antibodies

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          Cite BAZ2A Polyclonal Antibody

          • Antibody Testing Data (1)
          BAZ2A Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          BAZ2A Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          BAZ2A Antibody (61707) in WB

          BAZ2A antibody (pAb) tested by Western blot. BAZ2A antibody detection by Western blot. The analysis was performed using 40 µg of HeLa nuclear extract and BAZ2A at a 1:500 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          BAZ2A Antibody in Western Blot (WB)
          BAZ2A Polyclonal Antibody

          Product Details

          61707

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          This antibody was raised against a peptide within the N-terminal region of human BAZ2A.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Purification

          Antigen affinity chromatography, Affinity chromatography

          Storage buffer

          PBS, pH 7.5, with 30% glycerol

          Contains

          0.035% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2793744

          Target Information

          TIP 5 is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Bromodomain adjacent to zinc finger domain protein 2A; bromodomain adjacent to zinc finger domain, 2A; hWALp3; Transcription termination factor I-interacting protein 5; TTF-I interacting peptide 5; TTF-I-interacting protein 5

          View more View less

          Gene Aliases: BAZ2A; KIAA0314; TIP5; WALp3

          View more View less

          UniProt ID: (Human) Q9UIF9

          View more View less

          Entrez Gene ID: (Human) 11176

          View more View less

          Function(s)
          RNA polymerase I CORE element sequence-specific DNA binding RNA binding protein binding zinc ion binding ligand-dependent nuclear receptor binding histone binding lysine-acetylated histone binding chromatin/chromatin-binding, or -regulatory protein
          Process(es)
          chromatin silencing at rDNA DNA methylation chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated histone deacetylation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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