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Invitrogen
BDKRB2 Polyclonal Antibody
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Product Details
PA5-50488
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues near the C terminal of human bradykinin receptor B2
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total BDKRB2 protein.
Target Information
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-2 bradykinin receptor gene; B2 bradykinin receptor; B2-bradykinin receptor gene; B2R; BK-2 receptor; BK-2R; BK-2Rs; DKFZp686O088; G-protein coupled receptor; kinin B2; unnamed protein product
Gene Aliases: B(2); B2; B2R; BDKRB2; BK-2; BK2; BK2R; BKR2; BRB2
UniProt ID: (Human) P30411, (Mouse) P32299
Entrez Gene ID: (Human) 624, (Mouse) 12062
protease binding
phosphatidylinositol phospholipase C activity
G-protein coupled receptor activity
bradykinin receptor activity
protein binding
type 1 angiotensin receptor binding
protein heterodimerization activity
signal transducer activity
beta-2 adrenergic receptor binding
G-protein coupled receptor
system process
smooth muscle contraction
inflammatory response
signal transduction
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
response to salt stress
regulation of vasoconstriction
vasoconstriction
vasodilation
regulation of vascular permeability
arachidonic acid secretion
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
acute inflammatory response to antigenic stimulus
response to stress
negative regulation of cell proliferation
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
negative regulation of blood pressure
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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