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Proteintech
BHLHA15 Polyclonal Antibody
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Product Details
25140-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BHLHA15 Fusion Protein Ag18199 (1-189 aa encoded by BC113394)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKTKNRPPR RRAPVQDTEA TPGEGTPDGS LPNPGPEPAK GLRSRPARAA ARAPGEGRRR RPGPSGPGGR RDSSIQRRLE SNERERQRMH KLNNAFQALR EVIPHVRADK KLSKIETLTL AKNYIKSLTA TILTMSSSRL PGLEGPGPKL YQHYQQQQQV AGGALGATEA QPQGHLQRYS TQIHSFREGT (1-189 aa encoded by BC113394)
Target Information
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family, member a15; Basic helix-loop-helix transcription factor (bHlH); bHLHa15; bHLHb8; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST-1; Muscle, intestine and stomach expression 1
Gene Aliases: 1810009C13Rik; bHlH; BHLHA15; BHLHB8; MIST-1; MIST1
UniProt ID: (Human) Q7RTS1, (Rat) P70562, (Mouse) Q9QYC3
Entrez Gene ID: (Human) 168620, (Rat) 25334, (Mouse) 17341
transcription from RNA polymerase II promoter
mitochondrial calcium ion transport
Golgi organization
G-protein coupled receptor signaling pathway
cell-cell signaling
negative regulation of myotube differentiation
calcium-mediated signaling
endoplasmic reticulum unfolded protein response
cellular response to glucose starvation
glucose homeostasis
positive regulation of transcription from RNA polymerase II promoter
intracellular distribution of mitochondria
cell maturation
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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