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Invitrogen
BHMT Polyclonal Antibody
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Product Details
PA5-21470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human BHMT. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HepG2, mouse liver.
Predicted reactivity: Mouse (95%), Rat (93%), Zebrafish (82%), Xenopus laevis (87%), Pig (95%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Betaine--homocysteine S-methyltransferase 1; epididymis secretory sperm binding protein Li 61p; unnamed protein product
Gene Aliases: BHMT; BHMT1; HEL-S-61p; hm:zehn2153; wu:fb53h01; wu:fb63c08; wu:fj64d01; zgc:123027
UniProt ID: (Human) Q93088, (Mouse) O35490, (Zebrafish) Q32LQ4
Entrez Gene ID: (Human) 635, (Mouse) 12116, (Zebrafish) 322228
protein methylation
cellular modified amino acid metabolic process
amino-acid betaine metabolic process
amino-acid betaine catabolic process
methionine biosynthetic process
methylation
S-adenosylmethionine metabolic process
regulation of homocysteine metabolic process
'de novo' L-methionine biosynthetic process
L-methionine salvage
S-methylmethionine cycle
type B pancreatic cell development
digestive system development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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