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          • Primary Antibodies ›
          • BIN2 Antibodies

          Proteintech

          BIN2 Polyclonal Antibody

          2 References
          View all (7) BIN2 antibodies

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          Cite BIN2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (13)
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 13

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          BIN2 Antibody (14245-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human spleen using 14245-1-AP (BIN2 antibody) at dilution of 1:100 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BIN2 Antibody in Western Blot (WB)
          BIN2 Antibody in Western Blot (WB)
          BIN2 Antibody in Immunoprecipitation (IP)
          BIN2 Polyclonal Antibody

          Product Details

          14245-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          BIN2 Fusion Protein Ag5502 (216-565 aa encoded by BC047686)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          30 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: LRDVFYREM SKLNHNLYEV MSKLEKQHSN KVFVVKGLSS SSRRSLVISP PVRTATVSSP LTSPTSPSTL SLKSESESVS ATEDLAPDAA QGEDNSEIKE LLEEEEIEKE GSEASSSEED EPLPACNGPA QAQPSPTTER AKSQEEVLPS STTPSPGGAL SPSGQPSSSA TEVVLRTRTA SEGSEQPKKR ASIQRTSAPP SRPPPPRATA SPRPSSGNIP SSPTASGGGS PTSPRASLGT GTASPRTSLE VSPNPEPPEK PVRTPEAKEN ENIHNQNPEE LCTSPTLMTS QVASEPGEAK KMEDKEKDNK LISADSSEGQ DQLQVSMVPE NNNLTAPEPQ EEVSTSENPQ L (216-565 aa encoded by BC047686)

          Target Information

          BAR proteins, which are characterized by a common N-terminal BAR domain, are a family of adaptor proteins implicated in a diverse set of cellular processes. BIN1 (bridging integrator 1) and BIN2 are BAR proteins. The human BIN2 gene is located at chromosome 4q22.1, and encodes a 565-amino acid protein with a predicted molecular weight of ~62 kDa. It shows preferential expression in hematopoietic tissues, with highest mRNA levels in spleen and peripheral blood leukocytes and also high levels in thymus, colon, and placenta. BIN2 has been shown to migrate with an apparent mobility of ~80 kDa, and interact with BIN1.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: BIN2; breast cancer associated protein BRAP1; Breast cancer-associated protein 1; Bridging integrator 2; unnamed protein product

          View more View less

          Gene Aliases: BIN2; BRAP-1; BRAP1

          View more View less

          UniProt ID: (Human) Q9UBW5

          View more View less

          Entrez Gene ID: (Human) 51411

          View more View less

          Function(s)
          protein binding phospholipid binding
          Process(es)
          phagocytosis, engulfment cell chemotaxis podosome assembly membrane tubulation
          It has to be done as per old AB suggested Products section.

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