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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 60 and 268 of BLMH (Uniprot ID#Q13867)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-34680 targets BLMH in WB applications and shows reactivity with Human samples.
The PA5-34680 immunogen is recombinant fragment corresponding to a region within amino acids 60 and 268 of BLMH (Uniprot ID#Q13867).
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BLM hydrolase; BMH
BH; BLMH; BMH