BMP-2/BMP-4 Monoclonal Antibody (100230)

receptor binding cytokine activity protein binding growth factor activity phosphatase activator activity co-receptor binding protein serine/threonine kinase activator activity receptor agonist activity BMP receptor binding heparin binding chemoattractant activity

negative regulation of transcription from RNA polymerase II promoter skeletal system development ossification osteoblast differentiation branching involved in ureteric bud morphogenesis response to hypoxia in utero embryonic development epithelial to mesenchymal transition positive regulation of protein phosphorylation chondrocyte differentiation myeloid leukocyte differentiation heart morphogenesis heart induction endodermal-mesodermal cell signaling aortic valve development atrioventricular valve morphogenesis endocardial cushion morphogenesis cardiac atrium formation endocardial cushion formation positive regulation of extracellular matrix constituent secretion proteoglycan metabolic process regulation of transcription, DNA-templated transcription from RNA polymerase II promoter inflammatory response Notch signaling pathway cell-cell signaling heart development positive regulation of cell proliferation negative regulation of cell proliferation response to bacterium organ morphogenesis gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of epithelial to mesenchymal transition negative regulation of steroid biosynthetic process positive regulation of phosphatase activity telencephalon development telencephalon regionalization negative regulation of cell-cell adhesion cell differentiation positive regulation of Wnt signaling pathway bone mineralization osteoclast differentiation positive regulation of cell migration positive regulation of bone mineralization BMP signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of epithelial cell differentiation protein destabilization negative regulation of aldosterone biosynthetic process positive regulation of osteoblast proliferation cardiocyte differentiation embryonic heart tube anterior/posterior pattern specification positive regulation of peroxisome proliferator activated receptor signaling pathway ameloblast differentiation odontogenesis of dentin-containing tooth positive regulation of odontogenesis regulation of odontogenesis of dentin-containing tooth positive regulation of apoptotic process positive regulation of MAPK cascade negative regulation of insulin-like growth factor receptor signaling pathway cell fate commitment positive regulation of cell differentiation negative regulation of fat cell differentiation positive regulation of fat cell differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of ossification negative regulation of cell cycle negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter negative regulation of smooth muscle cell proliferation astrocyte differentiation positive regulation of astrocyte differentiation mesenchymal cell differentiation inner ear development negative regulation of calcium-independent cell-cell adhesion negative regulation of muscle cell differentiation cartilage development cardiac muscle cell differentiation cardiac muscle tissue morphogenesis pericardium development corticotropin hormone secreting cell differentiation thyroid-stimulating hormone-secreting cell differentiation cardiac epithelial to mesenchymal transition bone development positive regulation of SMAD protein import into nucleus lung vasculature development mesenchyme development muscle tissue development positive regulation of cartilage development positive regulation of ERK1 and ERK2 cascade cellular response to growth factor stimulus cellular response to BMP stimulus mesenchymal cell proliferation involved in ureteric bud development negative regulation of canonical Wnt signaling pathway positive regulation of bone mineralization involved in bone maturation positive regulation of p38MAPK cascade positive regulation of odontoblast differentiation positive regulation of pri-miRNA transcription from RNA polymerase II promoter cardiac jelly development atrioventricular canal morphogenesis negative regulation of cortisol biosynthetic process regulation of cardiac muscle cell differentiation negative regulation of cardiac muscle cell differentiation angiogenesis blood vessel development metanephros development ureteric bud development mesoderm formation organ induction kidney development mesonephros development neural tube closure positive regulation of endothelial cell proliferation vasculature development endochondral ossification blood vessel endothelial cell proliferation involved in sprouting angiogenesis hematopoietic progenitor cell differentiation lymphoid progenitor cell differentiation renal system process secondary heart field specification outflow tract septum morphogenesis membranous septum morphogenesis muscular septum morphogenesis outflow tract morphogenesis sinoatrial node development aortic valve morphogenesis pulmonary valve morphogenesis endocardial cushion development epithelial to mesenchymal transition involved in endocardial cushion formation cardiac right ventricle morphogenesis apoptotic process involved in endocardial cushion morphogenesis cardiac septum development type B pancreatic cell development germ cell development endoderm development mesoderm development mesodermal cell fate determination cell proliferation post-embryonic development anterior/posterior axis specification specification of organ position regulation of cell fate commitment regulation of gene expression dorsal/ventral neural tube patterning pituitary gland development erythrocyte differentiation monocyte differentiation macrophage differentiation lung development embryonic limb morphogenesis regulation of BMP signaling pathway positive regulation of BMP signaling pathway negative regulation of BMP signaling pathway forebrain development positive regulation of protein binding negative regulation of chondrocyte differentiation positive regulation of collagen biosynthetic process negative regulation of T cell differentiation in thymus negative regulation of immature T cell proliferation in thymus embryonic hindlimb morphogenesis tendon cell differentiation deltoid tuberosity development regulation of protein import into nucleus odontogenesis auditory receptor cell differentiation embryonic digit morphogenesis camera-type eye development positive regulation of programmed cell death regulation of cell differentiation negative regulation of cell differentiation positive regulation of endothelial cell differentiation positive regulation of epidermal cell differentiation negative regulation of myoblast differentiation negative regulation of mitotic nuclear division negative regulation of striated muscle tissue development lung alveolus development mesodermal cell differentiation intermediate mesodermal cell differentiation camera-type eye morphogenesis embryonic morphogenesis anatomical structure formation involved in morphogenesis regulation of smooth muscle cell proliferation positive regulation of smooth muscle cell proliferation neuron fate commitment embryonic cranial skeleton morphogenesis embryonic skeletal system morphogenesis embryonic skeletal system development smooth muscle tissue development stem cell differentiation epithelial cell proliferation positive regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation positive chemotaxis smooth muscle cell differentiation regulation of smooth muscle cell differentiation negative regulation of multicellular organismal process positive regulation of cardiac muscle fiber development lens induction in camera-type eye embryonic skeletal joint morphogenesis cranial suture morphogenesis lung morphogenesis epithelium development bronchus development trachea development trachea formation epithelial tube branching involved in lung morphogenesis branching involved in prostate gland morphogenesis bud elongation involved in lung branching epithelial cell proliferation involved in lung morphogenesis bud dilation involved in lung branching prostate gland morphogenesis prostatic bud formation mammary gland formation epithelial-mesenchymal cell signaling negative regulation of prostatic bud formation regulation of branching involved in prostate gland morphogenesis regulation of morphogenesis of a branching structure coronary vasculature development regulation of cartilage development positive regulation of branching involved in lung morphogenesis pharyngeal arch artery morphogenesis negative regulation of thymocyte apoptotic process glomerular capillary formation negative regulation of glomerular mesangial cell proliferation nephric duct formation ureter morphogenesis negative regulation of mesenchymal cell proliferation involved in ureter development regulation of branching involved in ureteric bud morphogenesis negative regulation of branching involved in ureteric bud morphogenesis negative regulation of glomerulus development positive regulation of protein localization to nucleus regulation of miRNA transcription negative regulation of pri-miRNA transcription from RNA polymerase II promoter pericyte cell differentiation negative regulation of vascular smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis regulation of mesodermal cell differentiation negative regulation of metanephric S-shaped body morphogenesis negative regulation of metanephric comma-shaped body morphogenesis positive regulation of primary miRNA processing negative regulation of extrinsic apoptotic signaling pathway