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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide LQTLRAGDEGWLVL conjugated to KLH, corresponding to amino acids 184-197 of BMP8.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31216 detects BMP8 from rat, mouse, human samples.
PA1-31216 has been successfully used in ELISA, Western blot applications.
The PA1-31216 immunogen is: Synthetic peptide: LQTLRAGDEGWLVL conjugated to KLH, corresponding to amino acids 184-197 of BMP8.
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BMP-8; BMP-8B; BMP8; bone morphogenetic protein 8 (osteogenic protein 2); bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP2; osteogenic protein 2
BMP8; BMP8B; OP2; Op3