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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • BMP-7 Antibodies

          Bioss

          BMP7 Polyclonal Antibody

          View all (26) BMP-7 antibodies

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          Cite BMP7 Polyclonal Antibody

          • Antibody Testing Data (3)
          BMP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          BMP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          BMP7 Antibody (BS-2242R) in IHC (P)

          Formalin-fixed and paraffin embedded rabbit alveolar bone labeled with Anti-BMP7 Polyclonal Antibody, Unconjugated (bs-2242R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          BMP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BMP7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BMP7 Antibody in Western Blot (WB)
          BMP7 Polyclonal Antibody

          Product Details

          BS-2242R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Dog, Human, Mouse, Rabbit, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human BMP7, amino acids 293-350.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extra skeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: BMP; BMP-7; bone moorphogenic protein-7; Bone morphogenetic protein; Bone morphogenetic protein 7; OP-1; Osteogenic protein 1; RP11-560A15.5

          View more View less

          Gene Aliases: BMP-7; BMP7; OP-1; OP1

          View more View less

          UniProt ID: (Human) P18075, (Mouse) P23359

          View more View less

          Entrez Gene ID: (Rabbit) 100337873, (Human) 655, (Dog) 477270, (Mouse) 12162, (Rat) 85272

          View more View less

          Function(s)
          cytokine activity transforming growth factor beta receptor binding protein binding growth factor activity heparin binding BMP receptor binding growth factor
          Process(es)
          skeletal system development ossification metanephros development ureteric bud development mesoderm formation mesonephros development epithelial to mesenchymal transition axon guidance embryonic pattern specification negative regulation of striated muscle cell apoptotic process positive regulation of peptidyl-threonine phosphorylation positive regulation of pathway-restricted SMAD protein phosphorylation dendrite development embryonic limb morphogenesis positive regulation of bone mineralization BMP signaling pathway epithelial cell differentiation negative regulation of NF-kappaB transcription factor activity response to estradiol response to vitamin D positive regulation of heterotypic cell-cell adhesion protein localization to nucleus growth negative regulation of phosphorylation negative regulation of NF-kappaB import into nucleus odontogenesis of dentin-containing tooth regulation of apoptotic process positive regulation of apoptotic process steroid hormone mediated signaling pathway negative regulation of MAP kinase activity response to peptide hormone negative regulation of neuron differentiation positive regulation of osteoblast differentiation negative regulation of Notch signaling pathway negative regulation of cell cycle negative regulation of mitotic nuclear division negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter embryonic camera-type eye morphogenesis branching morphogenesis of an epithelial tube mesenchymal cell differentiation neuron projection morphogenesis cartilage development embryonic skeletal joint morphogenesis regulation of pathway-restricted SMAD protein phosphorylation SMAD protein signal transduction branching involved in salivary gland morphogenesis mesenchyme development negative regulation of cell death negative regulation of prostatic bud formation regulation of branching involved in prostate gland morphogenesis monocyte aggregation cellular response to hypoxia cellular response to BMP stimulus negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis negative regulation of glomerular mesangial cell proliferation metanephric mesenchyme morphogenesis nephrogenic mesenchyme morphogenesis metanephric mesenchymal cell proliferation involved in metanephros development positive regulation of dendrite development positive regulation of hyaluranon cable assembly regulation of removal of superoxide radicals positive regulation of brown fat cell differentiation eye development kidney development multicellular organism development pattern specification process salivary gland morphogenesis negative regulation of cell proliferation organ morphogenesis positive regulation of cell death cell differentiation tube morphogenesis regulation of phosphorylation regulation of MAPK cascade positive regulation of cell differentiation positive regulation of neuron differentiation cell development camera-type eye morphogenesis anatomical structure formation involved in morphogenesis negative regulation of neurogenesis
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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