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Invitrogen
BMPER Polyclonal Antibody
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FIGURE: 1 / 1
BMPER Antibody (PA5-19847) in WB
Western blot analysis of EBS E14 TG2A day O whole cell lysate using Product # PA5-19847, BMPER primary antibody at a dilution of 1 µg/mL. Blot treated with a secondary HRP-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:3000.
Product Details
PA5-19847
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Mouse BMPER.
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
For Western Blot, this antibody has non-specific bands at 37 kDa.
Heat mediated antigen retrieval recommended prior to tissue staining.
This antibody is predicted to react with rat, chicken, cow, dog, human, chimpanzee and rhesus monkey based on sequence homology.
Target Information
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP-Binding Endothelial Regulator Protein; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator; CRIM3; crossveinless-2; hCV-2; mCV2; Protein crossveinless-2
Gene Aliases: 3110056H04Rik; Bmper; Crim3; CV-2; Cv2
UniProt ID: (Mouse) Q8CJ69
Entrez Gene ID: (Mouse) 73230
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
regulation of endothelial cell migration
negative regulation of BMP signaling pathway
endothelial cell activation
endothelial cell differentiation
inner ear development
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of ERK1 and ERK2 cascade
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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