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Bethyl Laboratories
BRD2 Polyclonal Antibody
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FIGURE: 1 / 2
BRD2 Antibody (IHC-00612) in ICC/IF
Detection of human BRD2 by immunocytochemistry. Sample: Formaldehyde-fixed asynchronous HeLa cells. Antibody: Affinity purified rabbit anti-BRD2 (Product # IHC-00612) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG cross-adsorbed Antibody DyLight 594 used at a dilution of 1:100.
Product Details
IHC-00612
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 675 and 725 of human bromodomain containing 2.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Bovine, Dog, Horse, Guinea pig_10141, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee and Chinese hamster
Target Information
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bromodomain-containing protein 2; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; FLJ31942; O27.1.1; really interesting new gene 3 protein; RING3 protein
Gene Aliases: BRD2; D6S113E; FSH; FSRG1; KIAA9001; NAT; O27.1.1; RING3; RNF3
UniProt ID: (Human) P25440
Entrez Gene ID: (Human) 6046
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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