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Product Details
PA5-47670
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse BTN2A2/Butyrophilin 2 Gln29-Ser219
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610593
Product Specific Information
In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse (rm) BTN and rmBTNL2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: butyrophilin 2; Butyrophilin subfamily 2 member A2
Gene Aliases: Btn2; Btn2a2; D030063K05
UniProt ID: (Mouse) A4QPC6
Entrez Gene ID: (Mouse) 238555
negative regulation of phosphatidylinositol 3-kinase signaling
negative regulation of cellular metabolic process
positive regulation of regulatory T cell differentiation
negative regulation of activated T cell proliferation
negative regulation of cytokine secretion
negative regulation of T cell receptor signaling pathway
negative regulation of protein kinase B signaling
negative regulation of ERK1 and ERK2 cascade
negative regulation of G1/S transition of mitotic cell cycle
Performance Guarantee
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