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Bag1/RAP46 Polyclonal Antibody
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Product Details
BS-3664R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Bag1/RAP46, amino acids 201-274.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAG family molecular chaperone regulator 1; BAG-1; BAG-1L; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2 associated athanogene 1; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
Gene Aliases: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
negative regulation of protein phosphorylation
apoptotic process
neuron differentiation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
chaperone cofactor-dependent protein refolding
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
response to lithium ion
response to organic cyclic compound
response to nicotine
response to drug
protein folding
cell surface receptor signaling pathway
positive regulation of smooth muscle cell apoptotic process
protein stabilization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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