Hamburger Menu Button
Thermo Fisher Scientific Logo
登入
還沒有帳戶嗎 ? 立即註冊
  • 產品
    • Antibodies
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Cell Culture Media
    • Chemicals
    • Western Blot Products
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Greener Products
    • 查看所有產品類別
  • 應用
    • 生物製程
    • 細胞培養和轉染
    • 食品和飲料
    • 實驗室解決方案
    • 製藥和生物製藥
    • 即時定量PCR
    • 半導體分析
    • 臨床和診斷
    • 數位解決方案
    • 分子光譜、同位素與元素分析
    • 查看所有應用與技術
  • 服務
    • 360° CDMO 和 CRO 服務
    • CDMO 服务
    • 临床试验 CRO 服务
    • 客製化服務
    • 金融與租賃服務
    • 儀器服務
    • 實驗室資訊學
    • 授權與商業供應
    • 培訓服務
    • 查看所有服務
  • 支援
    • 線上訂購協助
    • 數位解決方案
    • 產品支持
    • 技術相關資訊
    • 培訓與教育
    • 查看所有協助與支援
  • 熱門商品
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • 我們的服務對象
    • 生物技術
    • 生物製藥
    • CDMO
    • 實驗室診斷
    • 工業與應用科學
  • 特價商品
  • 聯絡我們
  • 快速訂購
  • 訂單狀態與貨物追蹤
  • 文件和證書
Thermo Fisher Scientific Logo

Search

Search All
Search button
          • 訂單查詢
          • 快速訂購
          • 登入
            登入
            還沒有帳戶嗎 ? 立即註冊
            • 帳戶
            • 訂單
            • Connect: Lab, Data, Apps
            • 客製化產品與項目
            • 儀器管理
          • Primary Antibodies ›
          • Bax beta Antibodies

          Exalpha

          Bax-beta Polyclonal Antibody

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

          {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support
          Datasheet
          Certificates
          Protocols
          Questions & Answers
          Tech Support

          Cite Bax-beta Polyclonal Antibody

          Additional Information:
          {{banner.description}}
          {{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

          Product Details

          X1290P

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Mouse

          Host/Isotype

          Sheep / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide corresponding to amino acids 172 to 199 of theBax protein

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5-2 mg/mL

          Amount

          250 µg

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          PBS

          Contains

          0.08% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Positive control: MCF-7 cell line.

          This antibody can be used for Western blotting (0.5-1 µg/mL), immunohistochemistry on formalin/paraffain embedded tissues (1-2 µg/mL) and immunoprecipitation (2 µg/mg of protein lysate). Antibody reacts with mutant as well as wild-type p53 protein.

          Target Information

          Members of the Bcl-2 Family (including Bcl-2, Bcl-XLand Bax) play an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, Bax is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of Bax and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
          Let us know so we can reference it here.
          Cite this product

          Bioinformatics

          Protein Aliases: Apoptosis regulator BAX; Apoptosis regulator Bax cytoplasmic isoform beta; Bax beta; BaxB; BCL2 associated X protein; BCL2 associated X protein isoform beta

          View more View less

          Gene Aliases: Bax

          View more View less

          UniProt ID: (Mouse) Q07813

          View more View less

          Entrez Gene ID: (Mouse) 12028

          View more View less

          Function(s)
          protein binding lipid binding channel activity heat shock protein binding protein complex binding identical protein binding protein homodimerization activity protein heterodimerization activity chaperone binding BH domain binding BH3 domain binding
          Process(es)
          ovarian follicle development neuron migration leukocyte homeostasis T cell homeostatic proliferation B cell homeostasis B cell apoptotic process kidney development release of cytochrome c from mitochondria protein insertion into mitochondrial membrane involved in apoptotic signaling pathway blood vessel remodeling myeloid cell homeostasis B cell negative selection B cell homeostatic proliferation positive regulation of B cell apoptotic process glycosphingolipid metabolic process regulation of nitrogen utilization apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process obsolete transformed cell apoptotic process cellular response to DNA damage stimulus inner mitochondrial membrane organization outer mitochondrial membrane organization germ cell development spermatogenesis nervous system development sex differentiation mitochondrial fusion cell proliferation negative regulation of cell proliferation male gonad development extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c apoptotic mitochondrial changes fertilization response to wounding response to toxic substance response to salt stress post-embryonic development response to ionizing radiation establishment or maintenance of transmembrane electrochemical gradient response to gamma radiation positive regulation of calcium ion transport into cytosol hypothalamus development cerebral cortex development negative regulation of protein binding positive regulation of protein oligomerization negative regulation of endoplasmic reticulum calcium ion concentration release of matrix enzymes from mitochondria negative regulation of peptidyl-serine phosphorylation regulation of mammary gland epithelial cell proliferation cellular response to UV limb morphogenesis ectopic germ cell programmed cell death odontogenesis of dentin-containing tooth regulation of apoptotic process positive regulation of apoptotic process regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of protein homodimerization activity regulation of protein heterodimerization activity regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process mitochondrial fragmentation involved in apoptotic process development of secondary sexual characteristics cellular respiration retinal cell programmed cell death positive regulation of developmental pigmentation negative regulation of fibroblast proliferation spermatid differentiation post-embryonic camera-type eye morphogenesis response to axon injury homeostasis of number of cells homeostasis of number of cells within a tissue protein oligomerization protein homooligomerization positive regulation of release of sequestered calcium ion into cytosol neuron apoptotic process regulation of cell cycle regulation of mitochondrial membrane potential transmembrane transport Sertoli cell proliferation retina development in camera-type eye positive regulation of apoptotic process involved in mammary gland involution vagina development intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress thymocyte apoptotic process mitochondrion morphogenesis cellular response to organic substance intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of release of cytochrome c from mitochondria apoptotic signaling pathway extrinsic apoptotic signaling pathway extrinsic apoptotic signaling pathway in absence of ligand intrinsic apoptotic signaling pathway activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway positive regulation of endoplasmic reticulum unfolded protein response regulation of mitochondrial membrane permeability involved in apoptotic process positive regulation of mitochondrial membrane permeability involved in apoptotic process apoptotic process involved in patterning of blood vessels apoptotic process involved in embryonic digit morphogenesis regulation of mitochondrial membrane permeability involved in programmed necrotic cell death positive regulation of apoptotic DNA fragmentation retinal cell apoptotic process B cell receptor apoptotic signaling pathway negative regulation of apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway in absence of ligand positive regulation of intrinsic apoptotic signaling pathway
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          產品訂購 Plus Icon Minus Icon
          • 訂單狀態
          • 訂購協助
          • 快速訂購
          • 現貨供應中心
          • 電子採購
          支持 Plus Icon Minus Icon
          • 協助與支持
          • 聯絡我們
          • 技術支持中心
          • 搜尋文件和證書
          • 回報網站問題
          資源 Plus Icon Minus Icon
          • 學習中心
          • 促銷活動
          • 活動和網路研討會
          • 社群媒體
          關於 Thermo Fisher Plus Icon Minus Icon
          • 關於我們 關於我們
          • 人才招募 人才招募
          • 投資者資訊 投資者資訊
          • 新聞 新聞
          • 企業社會責任 企業社會責任
          • 商標
          • 政策和聲明
          品牌 Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Policy
          • Price & Freight Policy
          © 2006-2026 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          Taiwan flag icon
          Taiwan

          Your items have has been added!


          Host server : magellan-search-blue-67655d8755-x75fr:80/100.66.77.4:80.
          git-commit: dddaa802cd395f65bf1581942d0e97a089c38f41
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.46.0-Offline