Brachyury is a 435 amino acid containing embryonic nuclear transcription factor binding to the palindromic T-site. It binds to the T-box in the N-terminus to regulate the genes required for mesodermal differentiation. It is the earliest indicator of mesoderm formation and differentiation. Brachyury is expressed during gastrula and neurula stages in involuting mesoderm and in the notochord.
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Protein Aliases: Brachyury protein; Protein T; RP11-459F1.1; T brachyury homolog; T, brachyury homolog; T-box transcription factor T; TFT
Gene Aliases: SAVA; T; TBXT; TFT
UniProt ID: (Human) O15178
Entrez Gene ID: (Human) 6862