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C1 Inactivator Polyclonal Antibody
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Product Details
BS-6187R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SERPING1, amino acids 401-500.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; C1-inhibitor; C1Inh; complement component 1 inhibitor; epididymis secretory sperm binding protein; esterase inhibitor; IC1; plasma protease (C1) inhibitor precursor; Plasma protease C1 inhibitor; serine (or cysteine) peptidase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary); serine (or cysteine) proteinase inhibitor, clade G, member 1; serine/cysteine proteinase inhibitor clade G member 1; Serpin G1; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_1; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_2; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_3; serpin peptidase inhibitor clade G (C1 inhibitor) member 1 isoform SERPING1_4; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; serpin peptidase inhibitor, clade G, member 1; SERPING1; unnamed protein product
Gene Aliases: C1IN; C1INH; C1NH; HAE1; HAE2; SERPING1
UniProt ID: (Human) P05155, (Rat) Q6P734, (Mouse) P97290
Entrez Gene ID: (Human) 710, (Rat) 295703, (Mouse) 12258
negative regulation of complement activation, lectin pathway
blood coagulation
hemostasis
blood circulation
fibrinolysis
complement activation, classical pathway
aging
biological_process
negative regulation of endopeptidase activity
innate immune response
immune system process
negative regulation of peptidase activity
regulation of blood coagulation
negative regulation of complement activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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