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The protein encoded by this gene localizes to centrosomes and primary cilia and co-localizes with a marker for the mother centriole. This gene resides in a region of human chromosome 3 that is linked to morbid obesity. A homozygous knockout of the orthologous gene in mouse resulted in mice with morbid obesity, hyperphagy, glucose intolerance, and insulin resistance. Mutations in this gene cause morbid obesity and spermatogenic failure (MOSPGF). This gene has a pseudogene on human chromosome 2.
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Protein Aliases: centrosomal protein 19kDa; Centrosomal protein of 19 kDa; Cep19; testis specific protein
Gene Aliases: 1500031L02Rik; AI428934; AL022620; C3orf34; CEP19; HSD5; MOSPGF; RGD621352
UniProt ID: (Human) Q96LK0, (Mouse) Q9CQA8
Entrez Gene ID: (Human) 84984, (Mouse) 66994, (Rat) 192229
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