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Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C9orf86; GTP-binding protein Parf; GTPase; Partner of ARF; protein associated with ARF; putative GTP-binding protein Parf; RAB, member of RAS oncogene family-like 6; Rab-like GTP-binding protein 1C; Rab-like protein 1; Rab-like protein 6; RBEL1; unnamed protein product
Gene Aliases: B230208H17Rik; C9orf86; PARF; pp8875; RABL6; RBEL1; Rbel1a; Rbel1b; RGD1307615
UniProt ID: (Human) Q3YEC7, (Mouse) Q5U3K5
Entrez Gene ID: (Human) 55684, (Mouse) 227624, (Rat) 362084
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