Recommended positive controls: Raji, HepG2, HepG2 whole cell extract (untreated), HepG2 whole cell extract (3 µM Thapsigargin treatment for 12 hr), HepG2 whole cell extract (3 µM Thapsigargin treatment for 24 hr), Huh-7 (untreated), Huh-7 (3 µM Thapsigargin treatment for 12 hr), Huh-7 (3 µM Thapsigargin treatment for 24 hr).
Predicted reactivity: Human (99%), Chimpanzee (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a subunit of nuclear domain 10 (ND10) bodies. ND10 bodies are nuclear domains appearing immunohistochemically as ten dots per nucleus. They are believed to be associated with the nuclear matrix on the basis of their resistance to nuclease digestion and salt extraction. ND10 proteins are removed from the nucleus by herpes simplex virus-1 infection and may have a role in viral life cycles.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antigen nuclear dot 52 kDa protein; Calcium-binding and coiled-coil domain-containing protein 2; NDP52; Nuclear domain 10 protein 52; nuclear domain 10 protein 52 like 1; Nuclear domain 10 protein NDP52; Nuclear dot protein 52
Gene Aliases: 2410154J16Rik; C77254; CALCOCO2; NDP52; Ndp52l1