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Immunogen sequence: RGEAYVCALS EFVDPSSLTA REEHFPSAHA TEILARFPCK ENPDNLSDFR EEVSRRLRYE SQ
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.
CALHM2, also named as FAM26B, is a pore-forming subunit of a voltage-gated ion channel. It is a critical ATP-releasing channel that modulates neural activity and as a potential risk factor of depression. There are three isoforms of CALHM2 with calculated MW 36 kDa, 24 kDa and 22 kDa. It is about 32-36 kDa in western blot with membrane protein extracted lysate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Calcium homeostasis modulator protein 2; family with sequence similarity 26, member B; Protein FAM26B
Gene Aliases: 2810048G17Rik; CALHM2; FAM26B; RGD1308276
UniProt ID: (Human) Q9HA72, (Rat) Q5RJQ8, (Mouse) Q8VEC4
Entrez Gene ID: (Human) 51063, (Rat) 294019, (Mouse) 72691
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