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Agrisera
CALS12/PMR4/Callose synthase 12 Polyclonal Antibody
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FIGURE: 1 / 1
CALS12/PMR4/Callose synthase 12 Antibody (AS21-4567) in WB
Samples: 1:Col-0 – Total protein extract 2:pmr 4-1/cals 12 – Total protein extract 3:Col-0 – soluble protein fraction (S 100) 4:pmr 4-1/cals 12 – soluble protein fraction (S 100) 5:Col-0 – microsomal protein fraction (P 100/M) 6:pmr 4-1/cals 12 – microsomal protein fraction (P 100/M) Total proteins were isolated from 60 Arabidopsis thaliana seedlings (10-day-old) of Col-0 (wild- type; lanes 1,3,5) and pmr 4... View More
Product Details
AS21-4567
Product Specifications
Species Reactivity
Plant
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
KLH-conjugated peptide derived from Arabidopsis thaliana CALS12 protein sequence.
Conjugate
Form
Lyophilized
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
Target Information
CALS12 encodes a large integral membrane callose synthase that localizes predominantly to the plasma membrane (and is also reported in Golgi-associated fractions), where it functions within a 1,3-beta-D-glucan synthase complex to polymerize callose for deposition at the cell wall-plasma membrane interface and at plasmodesmata. The protein is predicted to be multi-pass, with multiple C-terminal transmembrane helices anchoring a substantial cytosolic catalytic region characteristic of glucan synthase-like/glycosyltransferase enzymes. Biologically, CALS12-dependent callose accumulation contributes to regulated cell-to-cell connectivity by modulating plasmodesmatal permeability and reinforces local wall barriers during stress; genetic and physiological studies support key roles in inducible callose deposition during pathogen challenge (impacting penetration resistance and defense signaling outputs) and in adaptive responses such as phosphate deficiency, where CALS12 is required for callose deposition in root hairs that supports phosphate acquisition and growth under low-phosphate conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATGSL05; ATGSL5; EED3; enhancer of edr1 3; GLUCAN SYNTHASE-LIKE 5; GSL5; PMR4; POWDERY MILDEW RESISTANT 4; T5L23.4
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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