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CAMSAP2 Polyclonal Antibody

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CAMSAP2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded mouse testis tissue slide using 17880-1-AP (CAMSAP2 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

CAMSAP2 Antibody in Western Blot (WB) — Mouse brain tissue were subjected to SDS PAGE followed by western blot with 17880-1-AP (CAMSAP2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

CAMSAP2 Antibody in Immunoprecipitation (IP) — IP result of anti-CAMSAP2 (IP:17880-1-AP, 4ug; Detection:17880-1-AP 1:3000) with PC-3 cells lysate 5000ug.

Product Details

17880-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000-1:8,000	View 7 publications 7 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	-	View 12 publications 12 publications
Immunoprecipitation (IP)	0.5-4.0 µg	-
Miscellaneous PubMed (Misc)	-	View 2 publications 2 publications

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	CAMSAP2 Fusion Protein Ag11794 (551-904 aa encoded by BC065508) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.39 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: KADVPVEKY DGESDKEQFD DDQKVCCGFF FKDDQKAEND MAMKRAALLE KRLRREKETQ LRKQQLEAEM EHKKEETRRK TEEERQKKED ERARREFIRQ EYMRRKQLKL MEDMDTVIKP RPQVVKQKKQ RPKSIHRDHI ESPKTPIKGP PVSSLSLASL NTGDNESVHS GKRTPRSESV EGFLSPSRCG SRNGEKDWEN ASTTSSVASG TEYTGPKLYK EPSAKSNKHI IQNALAHCCL AGKVNEGQKK KILEEMEKSD ANNFLILFRD SGCQFRSLYT YCPETEEINK LTGIGPKSIT KKMIEGLYKY NSDRKQFSHI PAKTLSASVD AITIHSHLWQ TKRPVTPKKL LPTKA (551-904 aa encoded by BC065508)

Target Information

CAMSAP2 gene ontology annotations related to this gene include neuron projection development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.

Journal of cell science

Pongrakhananon V,Wattanathamsan O,Takeichi M,Chetprayoon P,Chanvorachote P

Mon Oct 29 00:00:00 EDT 2018

Loss of CAMSAP3 promotes EMT via the modification of microtubule-Akt machinery.

Journal of cell science

Pongrakhananon V,Wattanathamsan O,Takeichi M,Chetprayoon P,Chanvorachote P

Mon Oct 29 00:00:00 EDT 2018

APC2 controls dendrite development by promoting microtubule dynamics.

Nature communications

Kahn OI,Schätzle P,van de Willige D,Tas RP,Lindhout FW,Portegies S,Kapitein LC,Hoogenraad CC

Tue Jul 17 00:00:00 EDT 2018

Structural centrosome aberrations promote non-cell-autonomous invasiveness.

The EMBO journal

Ganier O,Schnerch D,Oertle P,Lim RY,Plodinec M,Nigg EA

Wed May 02 00:00:00 EDT 2018

EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.

The Journal of cell biology

Yang C,Wu J,de Heus C,Grigoriev I,Liv N,Yao Y,Smal I,Meijering E,Klumperman J,Qi RZ,Akhmanova A

Mon Oct 02 00:00:00 EDT 2017

EB1 and EB3 regulate microtubule minus end organization and Golgi morphology.

The Journal of cell biology

Yang C,Wu J,de Heus C,Grigoriev I,Liv N,Yao Y,Smal I,Meijering E,Klumperman J,Qi RZ,Akhmanova A

Mon Oct 02 00:00:00 EDT 2017

Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk.

FEBS letters

Wei J,Xu H,Meng W

Tue Aug 01 00:00:00 EDT 2017

Noncentrosomal microtubules regulate autophagosome transport through CAMSAP2-EB1 cross-talk.

FEBS letters

Wei J,Xu H,Meng W

Tue Aug 01 00:00:00 EDT 2017

Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres.

Open biology

Goldspink DA,Rookyard C,Tyrrell BJ,Gadsby J,Perkins J,Lund EK,Galjart N,Thomas P,Wileman T,Mogensen MM

Wed Feb 01 00:00:00 EST 2017

Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres.

Open biology

Goldspink DA,Rookyard C,Tyrrell BJ,Gadsby J,Perkins J,Lund EK,Galjart N,Thomas P,Wileman T,Mogensen MM

Wed Feb 01 00:00:00 EST 2017

Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.

Journal of cell science

Noordstra I,Liu Q,Nijenhuis W,Hua S,Jiang K,Baars M,Remmelzwaal S,Martin M,Kapitein LC,Akhmanova A

Tue Nov 15 00:00:00 EST 2016

Sliding of centrosome-unattached microtubules defines key features of neuronal phenotype.

The Journal of cell biology

Rao AN,Falnikar A,O'Toole ET,Morphew MK,Hoenger A,Davidson MW,Yuan X,Baas PW

Mon May 09 00:00:00 EDT 2016

Dynein Regulator NDEL1 Controls Polarized Cargo Transport at the Axon Initial Segment.

Neuron

Kuijpers M,van de Willige D,Freal A,Chazeau A,Franker MA,Hofenk J,Rodrigues RJ,Kapitein LC,Akhmanova A,Jaarsma D,Hoogenraad CC

Wed Feb 03 00:00:00 EST 2016

Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Yau KW,Schätzle P,Tortosa E,Pagès S,Holtmaat A,Kapitein LC,Hoogenraad CC

Wed Jan 27 00:00:00 EST 2016

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.

Neuron

van Beuningen SFB,Will L,Harterink M,Chazeau A,van Battum EY,Frias CP,Franker MAM,Katrukha EA,Stucchi R,Vocking K,Antunes AT,Slenders L,Doulkeridou S,Sillevis Smitt P,Altelaar AFM,Post JA,Akhmanova A,Pasterkamp RJ,Kapitein LC,de Graaff E,Hoogenraad CC

Wed Dec 16 00:00:00 EST 2015

Katanin p80 regulates human cortical development by limiting centriole and cilia number.

Neuron

Hu WF,Pomp O,Ben-Omran T,Kodani A,Henke K,Mochida GH,Yu TW,Woodworth MB,Bonnard C,Raj GS,Tan TT,Hamamy H,Masri A,Shboul M,Al Saffar M,Partlow JN,Al-Dosari M,Alazami A,Alowain M,Alkuraya FS,Reiter JF,Harris MP,Reversade B,Walsh CA

Wed Dec 17 00:00:00 EST 2014

Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development.

Neuron

Yau KW,van Beuningen SF,Cunha-Ferreira I,Cloin BM,van Battum EY,Will L,Schätzle P,Tas RP,van Krugten J,Katrukha EA,Jiang K,Wulf PS,Mikhaylova M,Harterink M,Pasterkamp RJ,Akhmanova A,Kapitein LC,Hoogenraad CC

Wed Jun 04 00:00:00 EDT 2014

Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development.

Neuron

Wed Jun 04 00:00:00 EDT 2014

Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.

Developmental cell

Jiang K,Hua S,Mohan R,Grigoriev I,Yau KW,Liu Q,Katrukha EA,Altelaar AF,Heck AJ,Hoogenraad CC,Akhmanova A

Mon Feb 10 00:00:00 EST 2014

Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.

Developmental cell

Jiang K,Hua S,Mohan R,Grigoriev I,Yau KW,Liu Q,Katrukha EA,Altelaar AF,Heck AJ,Hoogenraad CC,Akhmanova A

Mon Feb 10 00:00:00 EST 2014

Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.

Molecular & cellular proteomics : MCP

Syred HM,Welburn J,Rappsilber J,Ohkura H

Fri Nov 01 00:00:00 EDT 2013

Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules.

Proceedings of the National Academy of Sciences of the United States of America

Tanaka N,Meng W,Nagae S,Takeichi M

Tue Dec 04 00:00:00 EST 2012

Bioinformatics

Protein Aliases: calmodulin regulated spectrin-associated protein 1-like 1; calmodulin regulated spectrin-associated protein family, member 2; Calmodulin-regulated spectrin-associated protein 1-like protein 1; Calmodulin-regulated spectrin-associated protein 2

Gene Aliases: 1600013L13Rik; 4930541M15Rik; CAMSAP1L1; CAMSAP2; KIAA1078; mKIAA1078; RGD1310950

UniProt ID: (Human) Q08AD1, (Mouse) Q8C1B1, (Rat) D4AEC2

Entrez Gene ID: (Human) 23271, (Mouse) 67886, (Rat) 289400

Function(s)

microtubule cytoskeleton organization regulation of organelle organization neuron projection development

Process(es)

protein binding calmodulin binding spectrin binding microtubule minus-end binding microtubule binding

CAMSAP2 Polyclonal Antibody

Product Details

17880-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

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