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This target displays homology in the following species: Dog: 92%; Guinea Pig: 92%; Human: 100%; Mouse: 85%; Rabbit: 92%; Rat: 85%
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta subunits. This protein may be important in determining sperm architecture and male fertility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: capping protein (actin filament) muscle Z-line, alpha 3; CapZ alpha-3; CP-alpha-3; epididymis secretory protein Li 86; F-actin capping protein alpha-3 subunit; F-actin-capping protein subunit alpha-3; Germ cell-specific protein 3; testis tissue sperm-binding protein Li 73n
Gene Aliases: CAPAA3; CAPPA3; CAPZA3; GSG3; HEL-S-86
UniProt ID: (Human) Q96KX2
Entrez Gene ID: (Human) 93661
Molecular Function: non-motor actin binding protein
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