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Proteintech
CARD9 Polyclonal Antibody
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Product Details
10669-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CARD9 Fusion Protein Ag1057 (193-492 aa encoded by BC008877)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SEEKGAALM RNRDLQLEID QLKHSLMKAE DDCKVERKHT LKLRHAMEQR PSQELLWELQ QEKALLQARV QELEASVQEG KLDRSSPYIQ VLEEDWRQAL RDHQEQANTI FSLRKDLRQG EARRLRCMEE KEMFELQCLA LRKDSKMYKD RIEAILLQME EVAIERDQAI ATREELHAQH ARGLQEKDAL RKQVRELGEK ADELQLQVFQ CEAQLLAVEG RLRRQQLETL VLSSDLEDGS PRRSQELSLP QDLEDTQLSD KGCLAGGGSP KQPFAALHQE QVLRNPHDAG PAGLPGIGAV C (193-492 aa encoded by BC008877)
Target Information
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: card 9; caspase recruitment domain family, member 9; caspase recruitment domain protein 9; Caspase recruitment domain-containing protein 9; hCARD9; rCARD9; RP11-413M3.9
Gene Aliases: CANDF2; CARD9; Gm782; hCARD9
UniProt ID: (Human) Q9H257, (Rat) Q9EPY0, (Mouse) A2AIV8
Entrez Gene ID: (Human) 64170, (Rat) 64171, (Mouse) 332579
stimulatory C-type lectin receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
response to fungus
response to peptidoglycan
response to muramyl dipeptide
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
positive regulation of stress-activated MAPK cascade
response to drug
regulation of tumor necrosis factor biosynthetic process
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
response to exogenous dsRNA
regulation of interleukin-2 biosynthetic process
innate immune response
regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
defense response to virus
positive regulation of innate immune response
positive regulation of NF-kappaB transcription factor activity
immune system process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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