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OriGene
CASR Polyclonal Antibody
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FIGURE: 1 / 1
CASR Antibody (TA890014) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CASR(RC211229, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CASR rab. Positive lysates LY400136 (100 µg) and LC400136 (20 µg) can be purchased separately from OriGene.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
TA890014
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein of human CASR
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.22 mg/mL
Amount
222 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca sensing receptor; calcium receptor|CaR; CaSR antibody; parathyroid Ca(2+)-sensing receptor 1; parathyroid cell calcium-sensing receptor 1
Gene Aliases: CAR; EIG8; FHH; FIH; GPRC2A; hCasR; HHC; HHC1; HYPOC1; NSHPT; PCAR1
UniProt ID: (Human) P41180
Entrez Gene ID: (Human) 846
ossification
response to ischemia
detection of calcium ion
cellular calcium ion homeostasis
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
JNK cascade
chemosensory behavior
positive regulation of cell proliferation
anatomical structure morphogenesis
response to metal ion
positive regulation of insulin secretion
bile acid secretion
cellular response to hepatocyte growth factor stimulus
vasodilation
positive regulation of vasoconstriction
branching morphogenesis of an epithelial tube
positive regulation of positive chemotaxis
response to calcium ion
regulation of calcium ion transport
fat pad development
positive regulation of ERK1 and ERK2 cascade
cellular response to vitamin D
cellular response to glucose stimulus
cellular response to low-density lipoprotein particle stimulus
cellular response to hypoxia
response to fibroblast growth factor
positive regulation of calcium ion import
regulation of presynaptic membrane potential
positive regulation of NLRP3 inflammasome complex assembly
cellular response to peptide
chloride transmembrane transport
positive regulation of intracellular signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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