Immunogen sequence: TPFHIQAEVT MKTNFFGTRD VCTELLPLIK PQGRVVNVSS IMSVRALKSC SPELQQKFRS ETITEEELVG LMNKFVE
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q.
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Protein Aliases: 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 20-beta-hydroxysteroid dehydrogenase; carbonyl reductase (NADPH) 1; Carbonyl reductase [NADPH] 1; Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1); CBR; Cbr 1; hCBR1; member 1; NADPH-dependent carbonyl reductase 1; Prostaglandin 9-ketoreductase; Prostaglandin-E(2) 9-reductase; SDR21C1; short chain dehydrogenase/reductase family 21C; Short chain dehydrogenase/reductase family 21C member 1; short chain dehydrogenase/reductase family 21C, member 1
Gene Aliases: AW261796; CBR; CBR1; CR; CRN; hCBR1; SDR21C1