The antibody detects endogenous levels of total CCBL1 protein.
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
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Protein Aliases: beta-lysase, kidney; cysteine conjugate beta lyase 1; cysteine conjugate-beta lyase 1; cysteine conjugate-beta lyase, cytoplasmic; cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase); Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; Glutamine--phenylpyruvate transaminase; glutamine-phenylpyruvate aminotransferase; GTK; KAT1; KATI; kyneurenine aminotransferase; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; kynurenine aminotransferase/glutamine transaminase K; Kynurenine--oxoglutarate transaminase 1; Kynurenine--oxoglutarate transaminase 1, mitochondrial; Kynurenine--oxoglutarate transaminase I
Gene Aliases: CCBL1; GTK; Kat; KAT1; KATI; KYAT1